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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASS4
All Species:
10
Human Site:
T246
Identified Species:
22
UniProt:
Q9NQ75
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ75
NP_001157588.1
786
87144
T246
K
S
E
W
I
Y
D
T
P
V
S
P
G
K
A
Chimpanzee
Pan troglodytes
XP_001169779
786
87081
T246
K
S
E
W
I
Y
D
T
P
V
S
P
G
K
A
Rhesus Macaque
Macaca mulatta
XP_001090515
786
86837
T246
K
S
E
W
V
Y
D
T
P
V
S
P
G
K
A
Dog
Lupus familis
XP_534461
746
82524
N228
N
S
R
A
R
S
L
N
P
H
L
H
K
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q08EC4
804
88602
D244
Q
K
S
E
R
I
H
D
T
P
V
L
L
E
K
Rat
Rattus norvegicus
Q63767
968
104244
P369
Q
E
V
Y
D
T
P
P
M
A
V
K
G
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509857
821
90320
E276
Y
D
V
P
A
S
P
E
K
A
G
L
K
Q
A
Chicken
Gallus gallus
XP_417499
814
90427
D268
R
K
S
E
W
I
Y
D
I
P
I
S
P
E
K
Frog
Xenopus laevis
NP_001084484
853
95724
D257
L
P
P
P
R
K
S
D
W
I
Y
D
V
P
M
Zebra Danio
Brachydanio rerio
XP_001341038
774
86396
T253
P
K
D
I
D
S
T
T
A
L
Y
D
I
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782316
831
91548
K243
D
V
P
P
S
L
Q
K
A
K
D
E
K
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
93.6
64.2
N.A.
61
22.3
N.A.
51.4
43.4
38.5
29
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
98.8
96
72.3
N.A.
71.5
38
N.A.
66.8
60.5
55.6
45.2
N.A.
N.A.
N.A.
N.A.
39.7
P-Site Identity:
100
100
93.3
13.3
N.A.
0
6.6
N.A.
6.6
0
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
20
N.A.
13.3
13.3
6.6
20
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
19
19
0
0
0
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
19
0
28
28
0
0
10
19
0
0
0
% D
% Glu:
0
10
28
19
0
0
0
10
0
0
0
10
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
37
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% H
% Ile:
0
0
0
10
19
19
0
0
10
10
10
0
10
0
0
% I
% Lys:
28
28
0
0
0
10
0
10
10
10
0
10
28
28
19
% K
% Leu:
10
0
0
0
0
10
10
0
0
10
10
19
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% N
% Pro:
10
10
19
28
0
0
19
10
37
19
0
28
10
19
19
% P
% Gln:
19
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
10
0
28
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
37
19
0
10
28
10
0
0
0
28
10
0
10
0
% S
% Thr:
0
0
0
0
0
10
10
37
10
0
0
0
0
0
0
% T
% Val:
0
10
19
0
10
0
0
0
0
28
19
0
10
0
10
% V
% Trp:
0
0
0
28
10
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
28
10
0
0
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _